If you have an IIS and Exchange server and you find that when you try to send a message using the Createobject("CDO.Message") method you are receiving the "Access Denied" error, try the following steps.

1) Set the application pool to Exchange Application Pool under IIS - note this is only available under 2003.

2) Make sure the IUSR_servername user has full access to the Mailroot/Pickup directory (NTFS permissions).

3) If these don't work, you should give the SERVICE user full access to the Mailroot folder. That will do the job and allow you to send the email.